Crystal-Associated Colitis with Ulceration Leading to Hematochezia and Abdominal Pain

Crystal-Associated Colitis with Ulceration Leading to Hematochezia and Abdominal Pain

Lower GI bleeding is a common cause for hospitalization in adults. Medication-associated mucosal injury is an important clinical entity that can result in significant morbidity and mortality. We present the case of a 45-year-old woman with a 3-month history of intermittent abdominal cramping and rectal bleeding. Her medical history was extensive and included end-stage renal disease and a remote...

Infertility associated with hematochezia: A complication of perforated appendicitis

Introduction: Infection and inflammation of organs adjacent to gastrointestinal tract may cause a pathological connection. Patient: In this report, complicated appendicitis caused protrusion of right ovary and tube into the sigmoid colon of a 40-year-old infertile woman. The mass appearing as a polypoid lesion during colonoscopy caused abdominal pain and bleeding and proved to be right adnexa p...

Hematochezia Associated with Sevalamer-Induced Mucosal Injury

We present a case of a 61-year-old woman with end-stage renal disease (ESRD) who developed painless hematochezia following initiation of anticoagulation. Work-up revealed a large ulceration in the sigmoid colon, and histologic images revealed sevelamer crystals embedded in the colonic mucosa, consistent with sevelamer crystal-mediated injury. This is a novel cause of gastrointestinal hemorrhage...

Causes of hematochezia and hemorrhagic antibiotic-associated colitis in children and adolescents

Diseases causing hematochezia range from benign to potentially life-threatening. Systematic pediatric data on the causes of hematochezia are scarce. We studied the underlying causes and long-term outcome of hematochezia in children. We further investigated the relevance of antibiotic-associated hemorrhagic colitis in children, especially if caused by Klebsiella oxytoca.Infants, children, and ad...

Isolated Splenic Metastasis Presenting with Continuous Fever and Abdominal Pain